Single molecule studies of DNA repair

Ingrid Tessmer

Welcome to the Tessmer laboratory. Our work aims at understanding DNA repair processes at the level of the individual molecules. In particular, we are interested in general and specific features of DNA damage recognition and verification strategies employed by different DNA repair systems. Our research focuses on lesion search and recognition strategies in base excision repair (BER), in nucleotide excision repair (NER), and by the direct damage reversal protein O6-alkylguanine DNA alkyltransferase (AGT). In addition, we are interested in the interplay between these different systems that further enhance the remarkable versatility in DNA lesion repair.
Ingrid Tessmer

Rudolf Virchow Center
for Integrative and Translational Bioimaging • University of Würzburg
Josef-Schneider-Str. 2 / Building D15 • D-97080 Würzburg • Germany
Office: +49 (0)9 31 / 31-80425 • Fax: +49 (0)9 31 / 31-87320

Web page maintained by and comments to: ingrid.tessmer@virchow.uni-wuerzburg.de, last update September 2019